Mechanism of R factor-mediated chloramphenicol resistance.
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منابع مشابه
Episome-mediated Transfer of Drug Resistance in Enterobacteriaceae. 8. Six-drug-resistance R Factor.
Watanabe, Tsutomu (Keio University School of Medicine, Tokyo, Japan), Chizuko Ogata, and Sachiko Sato. Episome-mediated transfer of drug resistance in Enterobacteriaceae. VIII. Six-drug-resistance R factor. J. Bacteriol. 88:922-928. 1964.-The multiple-drug-resistant Escherichia coli strain isolated by Lebek in 1963 was found to transfer resistance to sulfonamide, streptomycin, chloramphenicol, ...
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A comparative study was done on the transfer frequency of R factors from 90 strains of multiple drug-resistant Aerobacter and 81 strains of Klebsiella to Escherichia coli CSH-2 (F(-), met(-), pro(-), Nal-r). The most common resistance patterns for the Aerobacter isolants were ampicillin streptomycin chloramphenicol tetracycline and ampicillin streptomycin chloramphenicol tetracycline kanamycin ...
متن کاملResistance to fusidic acid in Escherichia coli mediated by the type I variant of chloramphenicol acetyltransferase. A plasmid-encoded mechanism involving antibiotic binding.
Plasmid-encoded fusidic acid resistance in Escherichia coli is mediated by a common variant of chloramphenicol acetyltransferase (EC 2.3.1.28), an enzyme which is an effector of chloramphenicol resistance. Resistance to chloramphenicol is a consequence of acetylation of the antibiotic catalysed by the enzyme and the failure of the 3-acetoxy product to bind to bacterial ribosomes. Cell-free coup...
متن کاملR factor infection of Escherichia coli lyophilized in 1946.
remain ill-defined. The first R factor described, and most of those studied subsequently in Japan (T. Watanabe, Bacteriol. Rev. 27:87, 1963), mediated resistance to sulfonamides (SU), streptomycin (SM), tetracycline (TC), and chloramphenicol (CM). These results, and the lack of evidence that this pattern of resistance had gradually accumulated in Japan, suggested that this was the parent R fact...
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Riemerella anatipestifer causes serositis and septicaemia in domestic ducks, geese, and turkeys. Traditionally, the antibiotics were used to treat this disease. Currently, our understanding of R. anatipestifer susceptibility to chloramphenicol and the underlying resistance mechanism is limited. In this study, the cat gene was identified in 69/192 (36%) R. anatipestifer isolated from different r...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 95 5 شماره
صفحات -
تاریخ انتشار 1968